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It affects the amount of calcium found in your heart and muscle cells. This results in relaxation of blood vessels, which can reduce the amount of work the heart has to do. Diltiazem relieves different types of chest pain (angina); it is not a cure. Generic diltiazem tablets are available.<br> <h3><u>What should I tell my health care provider before I take this medicine?</u></h3><br> They need to know if you have any of these conditions:<br> • heart problems, low blood pressure, irregular heartbeat<br> • liver disease<br> • previous heart attack<br> • an unusual or allergic reaction to diltiazem, other medicines, foods, dyes, or preservatives<br> • pregnant or trying to get pregnant<br> • breast-feeding<br> <h3><u>How should I take this medicine?</u></h3><br> Take diltiazem tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Take diltiazem tablets on an empty stomach, at least 1 hour before or 2 hours after food. Do not significantly increase grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible. Take your doses at regular intervals. Do not take your medicine more often then directed. Do not stop taking except on your prescriber's advice.<br> <br> Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.<br> <h3><u>What if I miss a dose?</u></h3><br> If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. 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Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.<br> <h3><u>What side effects may I notice from taking diltiazem?</u></h3><br> Side effects that you should report to your prescriber or health care professional as soon as possible:<br> • confusion, mental depression<br> • fainting spells, lightheadedness<br> • redness, blistering, peeling or loosening of the skin, including inside the mouth<br> • skin rash, itching<br> • slow heartbeat, irregular heartbeat<br> • swelling of the feet and ankles<br> • unusual weakness or tiredness<br> • unusual bleeding or bruising, pinpoint red spots on the skin<br> <br> Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):<br> • constipation or diarrhea<br> • difficulty sleeping<br> • drowsiness or dizziness<br> • facial flushing<br> • headache<br> • nausea, vomiting<br> • sexual dysfunction<br> <h3><u>What should I watch for while taking diltiazem?</u></h3><br> Check your blood pressure and pulse rate regularly; this is important while you are taking diltiazem. 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